Efectividad del programa de mantenimiento con opioides para el tratamiento de su dependencia, en prisión / Effectiveness of opioid maintenance programs for treating drug dependence in prisons

Objetivos: Evaluar la efectividad del programa de mantenimiento con opioides en el tratamiento de su dependencia en prisiones españolas. Material y método: Se realizó una revisión bibliográfica narrativa en las siguientes bases de datos: PubMed, Cochrane, IBECS, LILACS y HealthCare. Se eligieron preferentemente todos aquellos ensayos clínicos, así como artículos de revisión sistemática y algún artículo que se consideró relevante por su contenido. El periodo de tiempo se limitó entre enero de 2011 y noviembre de 2021. El idioma de búsqueda fue: inglés, español y catalán. Se rechazaron los artículos repetidos y los que no tuvieron relación con los objetivos. Los criterios de búsqueda fueron: methadone AND prisons; opiate substitution treatment AND prisons; methadone AND buprenorphine; methadone OR buprenorphine; prisons AND Methadone AND buprenorphine. Resultados: Fueron seleccionados 20 artículos de 647 consultados, tras la aplicación de los filtros correspondientes y tras descartar los artículos duplicados. Discusión: Se evidenció una ligera mayor efectividad de la buprenorfina frente a la metadona. Se destacó una elevada prevalencia del programa, así como variedad de efectos adversos de la metadona. Su utilidad sobre el comportamiento obtiene disparidad de opiniones. Se anuncia la posibilidad de nuevas alternativas de tratamiento con un mejor control farmacológico. (AU)

Objectives: To evaluate the effectiveness of opioid maintenance programs in treating opioid dependence in Spanish prisons. Material and method: A narrative bibliographic review was carried out on the following databases: PubMed; Cochrane; IBECS; LILACS; HealthCare. All clinical trials were chosen as a preference, along with systematic review articles and some articles that were considered relevant for their content. The time period was limited to between January 2011 and November 2021. The languages chosen were English, Spanish and Catalan. Repeated articles and those that were not related to the objectives were rejected. The search criteria were: “methadone AND prisons”; “opiate substitution treatment AND prisons”; “methadone AND buprenorphine”; “methadone OR buprenorphine”; “prisons AND Methadone AND buprenorphine”. Results: 20 articles were selected out of 647 items consulted after applying the corresponding filters and after discarding duplicates. Discussion: There was a slightly greater effectiveness of buprenorphine versus methadone. The high prevalence of the program was highlighted, as well as the variety of adverse effects of methadone. Usefulness with regard to inmates’ behavior showed a range of opinions. The possibility of new treatment alternatives with better pharmacological control is mentioned. (AU)

Effectiveness of opioid maintenance programs for treating drug dependence in prisons.

OBJECTIVES: To evaluate the effectiveness of opioid maintenance programs in treating opioid dependence in Spanish prisons. MATERIAL AND METHOD: A narrative bibliographic review was carried out on the following databases: PubMed; Cochrane; IBECS; LILACS; HealthCare. All clinical trials were chosen as a preference, along with systematic review articles and some articles that were considered relevant for their content. The time period was limited to between January 2011 and November 2021. The languages chosen were English, Spanish and Catalan. Repeated articles and those that were not related to the objectives were rejected. The search criteria were: "methadone AND prisons"; "opiate substitution treatment AND prisons"; "methadone AND buprenorphine"; "methadone OR buprenorphine"; "prisons AND Methadone AND buprenorphine". RESULTS: 20 articles were selected out of 647 items consulted after applying the corresponding filters and after discarding duplicates. DISCUSSION: There was a slightly greater effectiveness of buprenorphine versus methadone. The high prevalence of the program was highlighted, as well as the variety of adverse effects of methadone. Usefulness with regard to inmates' behavior showed a range of opinions. The possibility of new treatment alternatives with better pharmacological control is mentioned.